What does vedolizumab mean?

Definitions for vedolizumab
vedolizum·ab

This dictionary definitions page includes all the possible meanings, example usage and translations of the word vedolizumab.

Wiktionary

  1. vedolizumabnoun

    A monoclonal antibody under investigation for the treatment of ulcerative colitis and Crohn's disease.

Wikidata

  1. Vedolizumab

    Vedolizumab is a monoclonal antibody being developed by Millennium Pharmaceuticals, Inc. for the treatment of ulcerative colitis and Crohn's disease. It binds to integrin α4β7. The cell line was discovered by Dr. Andrew Lazarovits and Dr. Robert Colvin as the murine MLN0002 homologue. Their discovery of the mouse equivalent of this antibody—originally applied to anti-rejection strategies in kidney transplantation—was published in the journal Nature, in 1996. The research was conducted at Massachusetts General Hospital in Boston, MA. Dr. Lazarovits and Dr. Colvin's cell line was subsequently licensed to Millennium Pharmaceuticals of Boston for further development. Vedolizumab has been in Phase III clinical trials since 2009, and has recently met critical endpoints. Reports indicate that Vedolizumab was found safe and highly effective for inducing and maintaining clinical remission in patients with moderate to severe ulcerative colitis. It looks like it will be an effective abiologic agent without some of the toxicity issues previously seen with anti-TNF drugs. Vedolizumab is often associated with the α4-integrin drug, Tysabri. They are, however, entirely different drugs, with separate mechanisms of action. Although there are symptoms of progressive multifocal leukoencephalopathy found in Tysabri, Dr. Brian Faegan, head researcher, reported an absence of any instances of PML in the Gemini Trial, which is a particularly important finding.

How to pronounce vedolizumab?

How to say vedolizumab in sign language?

Numerology

  1. Chaldean Numerology

    The numerical value of vedolizumab in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of vedolizumab in Pythagorean Numerology is: 4


Translations for vedolizumab

From our Multilingual Translation Dictionary

Get even more translations for vedolizumab »

Translation

Find a translation for the vedolizumab definition in other languages:

Select another language:

  • - Select -
  • 简体中文 (Chinese - Simplified)
  • 繁體中文 (Chinese - Traditional)
  • Español (Spanish)
  • Esperanto (Esperanto)
  • 日本語 (Japanese)
  • Português (Portuguese)
  • Deutsch (German)
  • العربية (Arabic)
  • Français (French)
  • Русский (Russian)
  • ಕನ್ನಡ (Kannada)
  • 한국어 (Korean)
  • עברית (Hebrew)
  • Gaeilge (Irish)
  • Українська (Ukrainian)
  • اردو (Urdu)
  • Magyar (Hungarian)
  • मानक हिन्दी (Hindi)
  • Indonesia (Indonesian)
  • Italiano (Italian)
  • தமிழ் (Tamil)
  • Türkçe (Turkish)
  • తెలుగు (Telugu)
  • ภาษาไทย (Thai)
  • Tiếng Việt (Vietnamese)
  • Čeština (Czech)
  • Polski (Polish)
  • Bahasa Indonesia (Indonesian)
  • Românește (Romanian)
  • Nederlands (Dutch)
  • Ελληνικά (Greek)
  • Latinum (Latin)
  • Svenska (Swedish)
  • Dansk (Danish)
  • Suomi (Finnish)
  • فارسی (Persian)
  • ייִדיש (Yiddish)
  • հայերեն (Armenian)
  • Norsk (Norwegian)
  • English (English)

Word of the Day

Would you like us to send you a FREE new word definition delivered to your inbox daily?

Please enter your email address:


Citation

Use the citation below to add this definition to your bibliography:

Style:MLAChicagoAPA

"vedolizumab." Definitions.net. STANDS4 LLC, 2024. Web. 14 Nov. 2024. <https://www.definitions.net/definition/vedolizumab>.

Discuss these vedolizumab definitions with the community:

0 Comments

    Are we missing a good definition for vedolizumab? Don't keep it to yourself...

    Free, no signup required:

    Add to Chrome

    Get instant definitions for any word that hits you anywhere on the web!

    Free, no signup required:

    Add to Firefox

    Get instant definitions for any word that hits you anywhere on the web!

    Quiz

    Are you a words master?

    »
    an attendant who carries the golf clubs for a player
    A fluster
    B abrade
    C caddie
    D excogitate

    Nearby & related entries:

    Alternative searches for vedolizumab: