What does oligoclonal bands mean?
Definitions for oligoclonal bands
oligo·clonal bands
This dictionary definitions page includes all the possible meanings, example usage and translations of the word oligoclonal bands.
Wikipedia
oligoclonal bands
Oligoclonal bands (OCBs) are bands of immunoglobulins that are seen when a patient's blood serum, or cerebrospinal fluid (CSF) is analyzed. They are used in the diagnosis of various neurological and blood diseases, especially in multiple sclerosis. Two methods of analysis are possible: (a) protein electrophoresis, a method of analyzing the composition of fluids, also known as "SDS-PAGE (sodium dodecyl sulphate polyacrylamide gel electrophoresis)/Coomassie blue staining", and (b) the combination of isoelectric focusing/silver staining. The latter is more sensitive.For the analysis of cerebrospinal fluid, a sample is first collected via lumbar puncture (LP). Normally it is assumed that all the proteins that appear in the CSF, but are not present in the serum, are produced intrathecally (inside the central nervous system). Therefore, it is normal to subtract bands in serum from bands in CSF when investigating CNS diseases. A sample of blood serum is usually obtained from a clotted blood sample taken around the time of the LP.
U.S. National Library of Medicine
Oligoclonal Bands
Multiple protein bands serving as markers of specific ANTIBODIES and detected by ELECTROPHORESIS of CEREBROSPINAL FLUID or serum. The bands are most often seen during inflammatory or immune processes and are found in most patients with MULTIPLE SCLEROSIS.
Numerology
Chaldean Numerology
The numerical value of oligoclonal bands in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of oligoclonal bands in Pythagorean Numerology is: 2
Translations for oligoclonal bands
From our Multilingual Translation Dictionary
- oligoclonal बैंडHindi
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"oligoclonal bands." Definitions.net. STANDS4 LLC, 2024. Web. 23 Nov. 2024. <https://www.definitions.net/definition/oligoclonal+bands>.
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