Definitions for nabumetone
nabume·tone

Princeton's WordNetRate this definition:0.0 / 0 votes

1. nabumetone, Relafennoun

   a nonsteroidal anti-inflammatory drug (trade name Relafen)

WikipediaRate this definition:0.0 / 0 votes

1. Nabumetone

   Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID). Nabumetone was developed by Beecham and first received regulatory approval in 1991. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran. Nabumetone is a nonacidic NSAID prodrug that is rapidly metabolized in the liver to the active metabolite, 6-methoxy-2-naphthyl acetic acid. As found with previous NSAIDs, nabumetone's active metabolite inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis). The active metabolite of nabumetone is felt to be the compound primarily responsible for therapeutic effect. Comparatively, the parent drug is a poor inhibitor of COX-2 byproducts, particularly prostaglandins. It may be less nephrotoxic than indomethacin. There are two known polymorphs of the compound.Nabumetone has little effect on renal prostaglandin secretion and less of an association with heart failure than other traditional drugs of the class. Effects of nabumetone on blood pressure control in hypertensive patients on ACE inhibitors is also good—equivalent to paracetamol.

ChatGPTRate this definition:0.0 / 0 votes

1. nabumetone

   Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain or inflammation caused by conditions such as arthritis. It works by reducing hormones in the body that cause inflammation and pain. It should be used under a doctor's supervision due to potential side effects and interactions with other medications.

WikidataRate this definition:0.0 / 0 votes

1. Nabumetone

   Nabumetone is a non-steroidal anti-inflammatory drug, the only 1-naphthaleneacetic acid derivative. Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran.

Matched Categories

1. • Nonsteroidal Anti-inflammatory

Usage in printed sourcesFrom: 

1. [["1972","1"],["1980","1"],["1983","3"],["1984","1"],["1985","3"],["1986","1"],["1987","133"],["1988","6"],["1989","51"],["1990","8"],["1991","6"],["1992","34"],["1993","75"],["1994","153"],["1995","106"],["1996","135"],["1997","196"],["1998","269"],["1999","222"],["2000","312"],["2001","200"],["2002","230"],["2003","192"],["2004","347"],["2005","251"],["2006","257"],["2007","188"],["2008","176"]]

How to pronounce nabumetone?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say nabumetone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of nabumetone in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of nabumetone in Pythagorean Numerology is: 2

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=nabumetone
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Nabumetone
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=nabumetone
5. ^ Usage in printed sources
   https://books.google.com/ngrams/graph?content=nabumetone