What does lysostaphin mean?
Definitions for lysostaphin
lysostaphin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word lysostaphin.
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Wiktionary
lysostaphinnoun
An antibiotic obtained from Staphylococcus simulans
Wikidata
Lysostaphin
Lysostaphin is a Staphylococcus simulans metalloendopeptidase. It can function as an antimicrobial against Staphylococcus aureus. Lysostaphin is a 27 KDa glycylglycine endopeptidase, an antibacterial enzyme which is capable of cleaving the crosslinking pentaglycin bridges in the cell wall of Staphylococci. Lysostaphin was first isolated from a culture of Staphylococcus simulans by Schindler and Schuhardt in 1964. S. aureus cell walls contain high proportions of pentaglycin, making lysostaphin a highly effective agent against both actively growing and quiescent bacteria. Staphylococcal infections of both Staphylococcus aureus and Staphylococcus epidermidis continue to be a major issue in clinical settings, particularly those with implantable devices. Staphylococci cause a significant percentage of device infections, and like many other pathogens, rather than living as free planktonic cells within the host they have the ability to form a multilayered community of sessile bacteria cells known as a biofilm on implantable devices. Once a "Staphylococcal" biofilm has formed on an implanted medical device, it is difficult to disrupt due to its antibiotic resistance and protection against bacterial action.
U.S. National Library of Medicine
Lysostaphin
A 25-kDa peptidase produced by Staphylococcus simulans which cleaves a glycine-glcyine bond unique to an inter-peptide cross-bridge of the STAPHYLOCOCCUS AUREUS cell wall. EC 3.4.24.75.
Numerology
Chaldean Numerology
The numerical value of lysostaphin in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of lysostaphin in Pythagorean Numerology is: 5
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"lysostaphin." Definitions.net. STANDS4 LLC, 2025. Web. 13 Mar. 2025. <https://www.definitions.net/definition/lysostaphin>.
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