Definitions for g0 phase
g0 phase

WikipediaRate this definition:0.0 / 0 votes

1. G0 phase

   The G0 phase describes a cellular state outside of the replicative cell cycle. Classically, cells were thought to enter G0 primarily due to environmental factors, like nutrient deprivation, that limited the resources necessary for proliferation. Thus it was thought of as a resting phase. G0 is now known to take different forms and occur for multiple reasons. For example, most adult neuronal cells, among the most metabolically active cells in the body, are fully differentiated and reside in a terminal G0 phase. Neurons reside in this state, not because of stochastic or limited nutrient supply, but as a part of their developmental program. G0 was first suggested as a cell state based on early cell cycle studies. When the first studies defined the four phases of the cell cycle using radioactive labeling techniques, it was discovered that not all cells in a population proliferate at similar rates. A population's “growth fraction” – or the fraction of the population that was growing – was actively proliferating, but other cells existed in a non-proliferative state. Some of these non-proliferating cells could respond to extrinsic stimuli and proliferate by re-entering the cell cycle. Early contrasting views either considered non-proliferating cells to simply be in an extended G1 phase or in a cell cycle phase distinct from G1 – termed G0. Subsequent research pointed to a restriction point (R-point) in G1 where cells can enter G0 before the R-point but are committed to mitosis after the R-point. These early studies provided evidence for the existence of a G0 state to which access is restricted. These cells that do not divide further exit G1 phase to enter an inactive stage called quiescent stage.

WikidataRate this definition:4.2 / 33 votes

1. G0 phase

   The G0 phase or resting phase is a period in the cell cycle in which cells exist in a quiescent state. G0 phase is viewed as either an extended G1 phase, where the cell is neither dividing nor preparing to divide, or a distinct quiescent stage that occurs outside of the cell cycle. Some types of cells, such as nerve and heart muscle cells, become quiescent when they reach maturity but continue to perform their main functions for the rest of the organism's life. Multinucleated muscle cells that do not undergo cytokinesis are also often considered to be in the G0 stage. On occasion, a distinction in terms is made between a G0 cell and a 'quiescent' cell, which will never enter the G1 phase, whereas other G0 cells may.

U.S. National Library of MedicineRate this definition:3.6 / 10 votes

1. G0 Phase

   A quiescent state of cells during G1 PHASE.

How to pronounce g0 phase?

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How to say g0 phase in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of g0 phase in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of g0 phase in Pythagorean Numerology is: 2

Examples of g0 phase in a Sentence

1. Jeffrey Barrett:

   We’re going to have to really contend with these new variants in the virus in the next phase of the pandemic, something happened that basically allowed a new constellation of mutations to arise.

2. Denise Faustman:

   In the phase I( preliminary) trial we demonstrated a statistically significant response to BCG, but our goal in( this trial) is to create a lasting therapeutic response, we will be working again with people who have had type 1 diabetes for many years. This is not a prevention trial ; instead, we are trying to create a regimen that will treat even advanced disease.

3. De Blasio:

   We're now actually in a position to start talking about opening things up, step by step, phase by phase.

4. Inga Beale in an interview:

   The market is going through a phase where it’s difficult to see too much growth if you’re an established player and therefore you will see this consolidation happening.

5. Larch Maxey:

   Right now we're in a phase of movement building, we're going to be doing more disruption in October in major cities around the world.

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/G0_Phase
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=g0 phase