What does erbb mean?
Definitions for erbb
erbb
This dictionary definitions page includes all the possible meanings, example usage and translations of the word erbb.
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Wikipedia
ErbB
The ErbB family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered member. In humans, the family includes Her1 (EGFR, ErbB1), Her2 (Neu, ErbB2), Her3 (ErbB3), and Her4 (ErbB4). The gene symbol, ErbB, is derived from the name of a viral oncogene to which these receptors are homologous: erythroblastic leukemia viral oncogene. Insufficient ErbB signaling in humans is associated with the development of neurodegenerative diseases, such as multiple sclerosis and Alzheimer's Disease, while excessive ErbB signaling is associated with the development of a wide variety of types of solid tumor.ErbB protein family signaling is important for development. For example, ErbB-2 and ErbB-4 knockout mice die at midgestation leads to deficient cardiac function associated with a lack of myocardial ventricular trabeculation and display abnormal development of the peripheral nervous system. In ErbB-3 receptor mutant mice, they have less severe defects in the heart and thus are able to survive longer throughout embryogenesis. Lack of Schwann cell maturation leads to degeneration of motor and sensory neurons. Excessive ErbB signaling is associated with the development of a wide variety of types of solid tumor. ErbB-1 and ErbB-2 are found in many human cancers, and their excessive signaling may be critical factors in the development and malignancy of these tumors.
ChatGPT
erbb
ERBB is a family of receptor tyrosine kinases that play critical roles in cellular growth, development and differentiation. They are involved in signaling pathways that regulate processes such as cell proliferation, survival, and migration. Dysregulation of ERBB receptors has been linked to various diseases, including cancer.
Numerology
Chaldean Numerology
The numerical value of erbb in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of erbb in Pythagorean Numerology is: 9
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"erbb." Definitions.net. STANDS4 LLC, 2025. Web. 5 Feb. 2025. <https://www.definitions.net/definition/erbb>.
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