Definitions for cofactor
ˈkoʊˌfæk tərco·fac·tor

Princeton's WordNetRate this definition:0.0 / 0 votes

1. cofactornoun

   a substance (as a coenzyme) that must join with another to produce a given result

WiktionaryRate this definition:0.0 / 0 votes

1. cofactornoun

   a contributing factor

2. cofactornoun

   a substance, especially a coenzyme or a metal, that must be present for an enzyme to function

3. cofactornoun

   a molecule that binds to and regulates the activity of a protein

4. cofactornoun

   the result of a number being divided by one of its factors

ChatGPTRate this definition:0.0 / 0 votes

1. cofactor

   A cofactor is a non-protein chemical compound or metallic ion that is required for an enzyme's activity as a catalyst, a substance that increases the rate of a chemical reaction. Cofactors can be considered "helper molecules" that assist in biochemical transformations. They may be either inorganic (e.g., metal ions and iron-sulfur clusters) or organic compounds (e.g., flavin and heme), but they are not composed of amino acids residues, distinguishing them from polypeptide chains.

WikidataRate this definition:0.0 / 0 votes

1. Cofactor

   A cofactor is a non-protein chemical compound that is bound to a protein and is required for the protein's biological activity. These proteins are commonly enzymes, and cofactors can be considered "helper molecules" that assist in biochemical transformations. Cofactors can be classified depending on how tightly they bind to an enzyme, with loosely bound cofactors termed coenzymes and tightly bound cofactors termed prosthetic groups. Some sources also limit the use of the term "cofactor" to inorganic substances. An inactive enzyme, without the cofactor is called an apoenzyme, while the complete enzyme with cofactor is the holoenzyme. Some enzymes or enzyme complexes require several cofactors. For example, the multienzyme complex pyruvate dehydrogenase at the junction of glycolysis and the citric acid cycle requires five organic cofactors and one metal ion: loosely bound thiamine pyrophosphate, covalently bound lipoamide and flavin adenine dinucleotide, and the cosubstrates nicotinamide adenine dinucleotide and coenzyme A, and a metal ion. Organic cofactors are often vitamins or are made from vitamins. Many contain the nucleotide adenosine monophosphate as part of their structures, such as ATP, coenzyme A, FAD, and NAD+. This common structure may reflect a common evolutionary origin as part of ribozymes in an ancient RNA world. It has been suggested that the AMP part of the molecule can be considered a kind of "handle" by which the enzyme can "grasp" the coenzyme to switch it between different catalytic centers.

Matched Categories

1. • Compound

Usage in printed sourcesFrom: 

1. [["1845","1"],["1866","3"],["1875","2"],["1877","1"],["1879","1"],["1882","4"],["1891","1"],["1892","1"],["1895","1"],["1899","2"],["1901","17"],["1904","6"],["1905","1"],["1909","15"],["1910","4"],["1911","1"],["1912","7"],["1916","10"],["1918","14"],["1920","14"],["1922","33"],["1923","11"],["1925","12"],["1926","11"],["1927","14"],["1928","4"],["1929","17"],["1930","35"],["1931","54"],["1932","5"],["1933","13"],["1934","4"],["1935","10"],["1936","17"],["1937","28"],["1938","40"],["1939","38"],["1940","6"],["1941","16"],["1942","68"],["1943","21"],["1944","27"],["1945","25"],["1946","50"],["1947","95"],["1948","67"],["1949","112"],["1950","113"],["1951","142"],["1952","96"],["1953","262"],["1954","207"],["1955","275"],["1956","204"],["1957","285"],["1958","530"],["1959","542"],["1960","578"],["1961","819"],["1962","1989"],["1963","923"],["1964","1300"],["1965","1509"],["1966","1159"],["1967","1512"],["1968","1240"],["1969","1187"],["1970","1792"],["1971","1819"],["1972","1477"],["1973","1919"],["1974","2046"],["1975","1804"],["1976","2497"],["1977","1870"],["1978","1879"],["1979","2375"],["1980","3872"],["1981","2669"],["1982","2542"],["1983","3246"],["1984","3698"],["1985","3717"],["1986","3660"],["1987","3921"],["1988","3822"],["1989","3692"],["1990","4238"],["1991","4735"],["1992","5431"],["1993","4962"],["1994","5058"],["1995","5981"],["1996","5831"],["1997","6753"],["1998","6600"],["1999","6435"],["2000","6173"],["2001","6054"],["2002","7590"],["2003","6042"],["2004","9522"],["2005","8679"],["2006","8873"],["2007","8248"],["2008","7263"]]

How to pronounce cofactor?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say cofactor in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of cofactor in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of cofactor in Pythagorean Numerology is: 9

Popularity rank by frequency of use

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=cofactor
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Cofactor
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=cofactor
5. ^ Usage in printed sources
   https://books.google.com/ngrams/graph?content=cofactor