What does cleavage stimulation factor mean?

Definitions for cleavage stimulation factor
cleav·age stim·u·la·tion fac·tor

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Wikipedia

  1. Cleavage stimulation factor

    Cleavage stimulatory factor or cleavage stimulation factor (CstF or CStF) is a heterotrimeric protein, made up of the proteins CSTF1 (55kDa), CSTF2 (64kDa) and CSTF3 (77kDa), totalling about 200 kDa. It is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA (mRNA) molecule. CstF is recruited by cleavage and polyadenylation specificity factor (CPSF) and assembles into a protein complex on the 3' end to promote the synthesis of a functional polyadenine tail, which results in a mature mRNA molecule ready to be exported from the cell nucleus to the cytosol for translation. The amount of CstF in a cell is dependent on the phase of the cell cycle, increasing significantly during the transition from G0 phase to S phase in mouse fibroblast and human splenic B cells.

U.S. National Library of Medicine

  1. Cleavage Stimulation Factor

    A RNA-binding protein that stimulates the cleavage of the 3' end of MRNA near the POLYADENYLATION site. It is a heterotrimer of 55-, 64- and 77-kDa subunits and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.

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Numerology

  1. Chaldean Numerology

    The numerical value of cleavage stimulation factor in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of cleavage stimulation factor in Pythagorean Numerology is: 2

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"cleavage stimulation factor." Definitions.net. STANDS4 LLC, 2024. Web. 24 Nov. 2024. <https://www.definitions.net/definition/cleavage+stimulation+factor>.

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