Definitions for bisphosphonate
bis·pho·s·pho·nate

WiktionaryRate this definition:0.0 / 0 votes

1. bisphosphonatenoun

   Any of a class of organic compounds having two phosphate groups attached to a single carbon atom

2. bisphosphonatenoun

   Several pharmaceuticals, having this structure, that are used to treat Paget's disease by restricting bone loss

WikipediaRate this definition:0.0 / 0 votes

1. Bisphosphonate

   Bisphosphonates are a class of drugs that prevent the loss of bone density, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. They are called bisphosphonates because they have two phosphonate (PO(OH)2) groups. They are thus also called diphosphonates (bis- or di- + phosphonate). Evidence shows that they reduce the risk of fracture in post-menopausal women with osteoporosis.Bone tissue undergoes constant remodeling and is kept in balance (homeostasis) by osteoblasts creating bone and osteoclasts destroying bone. Bisphosphonates inhibit the digestion of bone by encouraging osteoclasts to undergo apoptosis, or cell death, thereby slowing bone loss.The uses of bisphosphonates include the prevention and treatment of osteoporosis, Paget's disease of bone, bone metastasis (with or without hypercalcemia), multiple myeloma, primary hyperparathyroidism, osteogenesis imperfecta, fibrous dysplasia, and other conditions that exhibit bone fragility.

WikidataRate this definition:0.0 / 0 votes

1. Bisphosphonate

   Bisphosphonates are a class of drugs that prevent the loss of bone mass, used to treat osteoporosis and similar diseases. They are the most commonly prescribed drugs used to treat osteoporosis. They are called bisphosphonates because they have two phosphonate groups and are similar in structure to pyrophosphate. Evidence shows that they reduce the risk of osteoporotic fracture in those who have had previous fractures. Bone undergoes constant turnover and is kept in balance by osteoblasts creating bone and osteoclasts destroying bone. Bisphosphonates inhibit the digestion of bone by encouraging osteoclasts to undergo apoptosis, or cell death, thereby slowing bone loss. The uses of bisphosphonates include the prevention and treatment of osteoporosis, osteitis deformans, bone metastasis, multiple myeloma, primary hyperparathyroidism, osteogenesis imperfecta, and other conditions that feature bone fragility.

Anagrams for bisphosphonate »

1. biphosphonates

How to pronounce bisphosphonate?

1. Alex

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   David

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   Mark

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   Daniel

   British

   Libby

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   Mia

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   Karen

   Australian

   Hayley

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How to say bisphosphonate in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of bisphosphonate in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of bisphosphonate in Pythagorean Numerology is: 5

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References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Bisphosphonate
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Bisphosphonate
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=bisphosphonate