What does amyloid precursor protein secretase mean?
Definitions for amyloid precursor protein secretase
amy·loid pre·cur·sor pro·tein sec·re·tase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word amyloid precursor protein secretase.
Wikidata
Amyloid precursor protein secretase
Secretases are enzymes that "snip" pieces off a longer protein that is embedded in the cell membrane. Among other roles in the cell, secretases act on the amyloid precursor protein to cleave the protein into three fragments. Sequential cleavage by β-secretase and γ-secretase produces the amyloid-β peptide fragment that aggregates into clumps called "plaques" in the brains of Alzheimer's disease patients. If α-secretase acts on APP first instead of BACE, no amyloid-β is formed because α-secretase recognizes a target protein sequence closer to the cell surface than BACE. The non-pathogenic middle fragment formed by an α/γ cleavage sequence is called P3.
Numerology
Chaldean Numerology
The numerical value of amyloid precursor protein secretase in Chaldean Numerology is: 5
Pythagorean Numerology
The numerical value of amyloid precursor protein secretase in Pythagorean Numerology is: 8
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"amyloid precursor protein secretase." Definitions.net. STANDS4 LLC, 2025. Web. 13 Mar. 2025. <https://www.definitions.net/definition/amyloid+precursor+protein+secretase>.
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