What does activin receptors, type ii mean?

Definitions for activin receptors, type ii
ac·tivin re·cep·tors, type ii

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Wikipedia

  1. activin receptors, type ii

    The activin type 2 receptors belong to a larger TGF-beta receptor family and modulate signals for transforming growth factor beta ligands. These receptors are involved in a host of physiological processes including, growth, cell differentiation, homeostasis, osteogenesis, apoptosis and many other functions. There are two activin type two receptors: ACVR2A and ACVR2B. Despite the large amount of processes that these ligands regulate, they all operate through essentially the same pathway: A ligand binds to a type 2 receptor, which recruits and trans-phosphorylates a type I receptor. The type I receptor recruits a receptor regulated SMAD (R-SMAD) which it phosphorylates. The RSMAD then translocates to the nucleus where it functions as a transcription factor.

U.S. National Library of Medicine

  1. Activin Receptors, Type II

    One of the two types of ACTIVIN RECEPTORS. They are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES. The major type II activin receptors are ActR-IIA and ActR-IIB.

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Numerology

  1. Chaldean Numerology

    The numerical value of activin receptors, type ii in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of activin receptors, type ii in Pythagorean Numerology is: 2

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