What does acitretin mean?

Definitions for acitretin
ac·itretin

This dictionary definitions page includes all the possible meanings, example usage and translations of the word acitretin.


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Wiktionary

  1. acitretinnoun

    A retinoid that is used to treat psoriasis.

Wikidata

  1. Acitretin

    Acitretin is a second-generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. Etretinate was discontinued because it had a narrow therapeutic index as well as a long elimination half-life, making dosing difficult. In contrast, acitretin's half-life is approximately 2 days. However, because acitretin can be reverse metabolised into etretinate which has an extremely long half-life, women must avoid becoming pregnant for at least 3 years after discontinuing acitretin. Therefore, acitretin is generally not recommended for women of child-bearing age with a risk of becoming pregnant. Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis. Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments. It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.

U.S. National Library of Medicine

  1. Acitretin

    An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of ETRETINATE with the advantage of a much shorter half-life when compared with etretinate.

Anagrams for acitretin »

  1. intricate

  2. triacetin

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Numerology

  1. Chaldean Numerology

    The numerical value of acitretin in Chaldean Numerology is: 8

  2. Pythagorean Numerology

    The numerical value of acitretin in Pythagorean Numerology is: 9

Popularity rank by frequency of use

acitretin#100000#242236#333333

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"acitretin." Definitions.net. STANDS4 LLC, 2024. Web. 23 Dec. 2024. <https://www.definitions.net/definition/acitretin>.

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