What does spherocytosis mean?
Definitions for spherocytosis
sphe·ro·cy·to·sis
This dictionary definitions page includes all the possible meanings, example usage and translations of the word spherocytosis.
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Wikipedia
Spherocytosis
Spherocytosis is the presence of spherocytes in the blood, i.e. erythrocytes (red blood cells) that are sphere-shaped rather than bi-concave disk shaped as normal. Spherocytes are found in all hemolytic anemias to some degree. Hereditary spherocytosis and autoimmune hemolytic anemia are characterized by having only spherocytes.
Wikidata
Spherocytosis
Spherocytosis is an auto-hemolytic anemia characterized by the production of red blood cells, or erythrocytes, that are sphere-shaped, rather than bi-concave disk shaped. Spherocytes are found in hereditary spherocytosis and autoimmune hemolytic anemia. It almost always refers to hereditary spherocytosis. This is caused by a molecular defect in one or more of the proteins of the red blood cell cytoskeleton, including, spectrin, ankyrin, Band 3, or Protein 4.2. Because the cell skeleton has a defect, the blood cell contracts to its most surface-tension efficient and least flexible configuration, a sphere. The sphere-shaped red blood cells are known as spherocytes. Though the spherocytes have a smaller surface area through which oxygen and carbon dioxide can be exchanged, they in themselves perform adequately to maintain healthy oxygen supplies. However, they have a high osmotic fragility--when placed into water, they are more likely to burst than normal red blood cells. These cells are more prone to physical degradation. They are most commonly found in immunologically-mediated hemolytic anemias and in hereditary spherocytosis, but the former would have a positive direct Coombs test and the latter would not. The misshapen but otherwise healthy red blood cells are mistaken by the spleen for old or damaged red blood cells and it thus constantly breaks them down, causing a cycle whereby the body destroys its own blood supply.
Numerology
Chaldean Numerology
The numerical value of spherocytosis in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of spherocytosis in Pythagorean Numerology is: 2
Translations for spherocytosis
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"spherocytosis." Definitions.net. STANDS4 LLC, 2024. Web. 5 Jun 2024. <https://www.definitions.net/definition/spherocytosis>.
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