What does nicotinamide-nucleotide adenylyltransferase mean?
Definitions for nicotinamide-nucleotide adenylyltransferase
nicoti·namide-nu·cleo·tide adeny·lyl·trans·ferase
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Wikipedia
Nicotinamide-nucleotide adenylyltransferase
In enzymology, nicotinamide-nucleotide adenylyltransferase (NMNAT) (EC 2.7.7.1) are enzymes that catalyzes the chemical reaction ATP + nicotinamide mononucleotide ⇌ {\displaystyle \rightleftharpoons } diphosphate + NAD+Thus, the two substrates of this enzyme are ATP and nicotinamide mononucleotide (NMN), whereas its two products are diphosphate and NAD+. This enzyme participates in nicotinate and nicotinamide metabolism. Humans have three protein isoforms: NMNAT1 (widespread), NMNAT2 (predominantly in brain), and NMNAT3 (highest in liver, heart, skeletal muscle, and erythrocytes). Mutations in the NMNAT1 gene lead to the LCA9 form of Leber congenital amaurosis. Mutations in NMNAT2 or NMNAT3 genes are not known to cause any human disease. NMNAT2 is critical for neurons: loss of NMNAT2 is associated with neurodegeneration. All NMNAT isoforms reportedly decline with age.
U.S. National Library of Medicine
Nicotinamide-Nucleotide Adenylyltransferase
An enzyme that catalyzes reversibly the transfer of the adenylyl moiety of ATP to the phosphoryl group of NMN to form NAD+ and pyrophosphate. The enzyme is found predominantly in the nuclei and catalyzes the final reaction in the major pathway for the biosynthesis of NAD in mammals. EC 2.7.7.1.
Numerology
Chaldean Numerology
The numerical value of nicotinamide-nucleotide adenylyltransferase in Chaldean Numerology is: 2
Pythagorean Numerology
The numerical value of nicotinamide-nucleotide adenylyltransferase in Pythagorean Numerology is: 7
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"nicotinamide-nucleotide adenylyltransferase." Definitions.net. STANDS4 LLC, 2024. Web. 5 May 2024. <https://www.definitions.net/definition/nicotinamide-nucleotide+adenylyltransferase>.
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