What does nalp3 mean?
Definitions for nalp3
nalp3
This dictionary definitions page includes all the possible meanings, example usage and translations of the word nalp3.
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Wikipedia
nalp3
NLR family pyrin domain containing 3 (NLRP3) (previously known as NACHT, LRR and PYD domains-containing protein 3 [NALP3] and cryopyrin), is a protein that in humans is encoded by the NLRP3 gene located on the long arm of chromosome 1.NLRP3 is expressed predominantly in macrophages and as a component of the inflammasome,: 436 detects products of damaged cells such as extracellular ATP and crystalline uric acid. Activated NLRP3 in turn triggers an immune response. Mutations in the NLRP3 gene are associated with a number of organ specific autoimmune diseases.
Wikidata
NALP3
NACHT, LRR and PYD domains-containing protein 3 or cryopyrin is a protein that in humans is encoded by the NLRP3 gene. The gene is also called cold induced autoinflammatory syndrome 1 and is located on the long arm of chromosome 1. Another name for the protein is caterpiller-like receptor 1.1. This gene encodes a pyrin-like protein which contains a pyrin domain, a nucleotide-binding site domain, and a leucine-rich repeat motif. This protein interacts with pyrin domain of apoptosis-associated speck-like protein containing a CARD. Proteins which contain the caspase recruitment domain, CARD, have been shown to be involved in inflammation and immune response. This protein may function as an activator of NF-κB signaling.
Numerology
Chaldean Numerology
The numerical value of nalp3 in Chaldean Numerology is: 8
Pythagorean Numerology
The numerical value of nalp3 in Pythagorean Numerology is: 7
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"nalp3." Definitions.net. STANDS4 LLC, 2024. Web. 21 May 2024. <https://www.definitions.net/definition/nalp3>.
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